08/31/2023
La Deeptech voit BIG, le rendez-vous national de l’entrepreneuriat deeptech
Pour sa 3e édition, La Deeptech voit BIG se transforme et devient la finale nationale de pitch de projets à fort impact !
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2023
October 2nd
October 6th
International course
Genome Instability and Human Disease
Genome instability is a hallmark of cancer cells but also a cause of genetic diseases in humans. Our understanding of the causal relationships between genome instability and the development of human diseases rely on our knowledge of the basic mechanisms of DNA and RNA metabolism, from the spatial genome organization to the chromatin landscape up to the regulation of genome expression during development or in response to genotoxic stress.
The dysfunctions of these basic mechanisms related to genome metabolism underlie human diseases including cancer, aging, neurological disorders and immune deficiency.
The main topics are:
- Basics mechanisms for maintaining genome stability (repair, replication, DNA damage signaling, spatial genome organization).
- Dysfunction of these pathways in human diseases (cancer, aging, immunodeficiency).
- Molecular signature of genome Instability.
The DNA damage response as anti-cancer therapeutic targets and tools for diagnostic/prognostic.
Course in
English
Registration deadline
Presentation
Objectives
This international course has two objectives:
- Gain knowledge of mechanisms ensuring genome stability, from fundamental molecular pathways (DNA replication, repair, transcription, genome organization) up to large scale approaches (molecular signature using NGS and proteomic).
- Highlight how a research continuum, from basic research to clinical and translational research, provides opportunities to solve human health issues.
The educational objectives are:
- Encourage the students to speak. Students will ensure the moderator role and introduce speakers + elevator speech
Train students to the evaluation process by awarding themselves the poster price.
Personal Work
- Chairman/Chairwoman activities
- Participation and scientific animation
- Elevator pitch
Documents & Links
Practical Informations
Practical Informations
Organization:
- Seminars by experts in the field of the mechanisms that maintain genome stability to large scale approaches (molecular signature using NGS and proteomic). Highlight how a research continuum, from basic research to clinical and translational research, provides opportunities to solve human health issues.
- Workshops: Career development, scientific communication, technological workshop, poster session, “elevator pitch”, “students will chair” session
- Poster prize
- Curie Museum visit.
Selection result
September 1, 2023
There is no registration fee for this course
Place
Institut Curie - Bâtiment de Biologie du Développement - Amphithéâtre
11 Rue Pierre et Marie Curie
75248 Paris cedex 05
France
75248 Paris cedex 05
France
Maximum Number of Participants
30 people
Number of Participants
30 participants
Selection Criteria
Selection on CV and recommendation letter.
Speakers
Speakers
Genevieve ALMOUZNI - FR
Anabelle DECOTTIGNIES - BE
Ludovic DERIANO - FR
Fumiko ESASHI - UK
Michaela FONTENAY - FR
Olivier HYRIEN - FR
Massimo LOPES - CH
Enzo POIRIER - FR
Beatrice RONDINELLI - FR
Filippo ROSSELLI - FR
Eli ROTHENBERG - US
Dominique STOPPA-LYONNET - FR
Terence STRICK - FR
Angela TADDEI - FR
Stephan VAGNER - FR
Wei YANG - US
Keynote speakers
John DIFFLEY – UK
Helle ULRICH - DE
This list of speakers may still change
Organizers
Chunlong Chen, unit UMR3244 « Dynamics of Genetic Information: fundamental bases and cancer (DIG-Cancer) », team leader « Replication program and genome instability », Institut Curie, Paris.
Valérie Borde, unit UMR3244 « Dynamics of Genetic Information: fundamental bases and cancer (DIG-Cancer) », team leader « Chromosome Dynamics and Recombination », Institut Curie, Paris.
Sarah Lambert, unit UMR3348 « Genome Integrity, RNA and Cancer », team leader « DNA Recombination, Replication and Genome Stability », Institut Curie, Orsay.
Raphaël Ceccaldi, unit U830 « Cancer, Heterogeneity, Instability and Plasticity - CHIP », team leader « Alternative DNA repair mechanisms in human cancers », Institut Curie, Paris.
Daniele Fachinetti, unit UMR 144 « Cell Biology and Cancer », team leader « Molecular Mechanisms of Chromosome Dynamics », Institut Curie, Paris.
Aura Carreira, CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA, Madrid.
Scientific Committee
Chunlong Chen, unit UMR3244 « Dynamics of Genetic Information: fundamental bases and cancer (DIG-Cancer) », team leader « Replication program and genome instability », Institut Curie, Paris.
Valérie Borde, unit UMR3244 « Dynamics of Genetic Information: fundamental bases and cancer (DIG-Cancer) », team leader « Chromosome Dynamics and Recombination », Institut Curie, Paris.
Sarah Lambert, unit UMR3348 « Genome Integrity, RNA and Cancer », team leader « DNA Recombination, Replication and Genome Stability », Institut Curie, Orsay.
Raphaël Ceccaldi, unit U830 « Cancer, Heterogeneity, Instability and Plasticity - CHIP », team leader « Alternative DNA repair mechanisms in human cancers », Institut Curie, Paris.
Daniele Fachinetti, unit UMR 144 « Cell Biology and Cancer », team leader « Molecular Mechanisms of Chromosome Dynamics », Institut Curie, Paris.
Aura Carreira, Centro de Biologia Molecular SEVERO OCHOA, Madrid.
Supported by
Organization
- Advanced Training Office - Institut Curie