March 16th
March 23rd
visuelEPI fev2022
International course


17th edition - From nuclear organization to metabolism and cell fate in normal state and diseases

The aim of this course is to provide an overview of epigenetic mechanisms and their links to gene expression and chromatin dynamics, in different systems. The diverse functions of the nucleus involving the genome and its organization will be discussed with an emphasis on technological limits and the new experimental approaches being developed today. Links between the disruption of nuclear functions and the development of human pathologies will be discussed. This year emphasis will be on the physiological and pathological aspects of epigenetics in relation with metabolism and maintenance of cell identity. 

The success of the course relies on the contributions of participants who are expected to be proactive and to participate in all of the events organized, including Poster sessions, Journal Club, "career development" workshop on Saturday morning and the "epi-Courses", such as the “Art & Science” workshop.

A special session will be devoted to 3 alumni students who have gone on to successful careers in the field of Epigenetics.

Please note that the registration deadline for master's students is September 30, 2021

Course in English
Registration deadline



Main topics discussed during the 17th Course on Epigenetics: metabolism and cell identity determination

- Epigenetics and Chromatin Dynamics
- Imaging the Nucleus and its functions
- Silencing, transcriptional landscapes and genomics
- Memory of transcriptional states, stem cells and reprogramming
- Epigenetics : quantitative approaches and theoretical models
- Maintenance of (Epi)genome integrity
- Epigenetics and Cancer

Discussion & Workshops

Round table for the “career development” workshop

Personal Work

1. POSTER SESSION: Presentation of participant's own scientific project with a poster,

2. JOURNAL CLUB: Participation in the Journal Club to both present and review key articles proposed by the speakers,

3. WORKSHOP: Participation in the "career development" workshop during the Saturday morning and the "epi-Courses" such as the “Art & Science” workshop.

ECTS Information


Exam & Evaluation

Evaluation will be based on the poster presentation, journal club and general participation all along the course.


Career development workshop

Practical Informations

Practical Informations

This course is open:

- to M2 or Ph. D students (up to 16) of Parisian universities: 5 positions reserved to M2 students from Sorbonne University

- to Master or Ph. D students from France at large and European universities (up to 16)

Registration deadline for master's students is September 30, 2021

Selection result
January 15, 2022
There is no registration fee for this course
Institut Curie - Bâtiment de Biologie du Développement - Amphithéâtre
11 rue Pierre et Marie Curie
75005 Paris

Maximum Number of Participants

32 people

Number of Participants

32 participants

Selection Criteria

Selection to the course will be based on CV and motivation statement.



Almouzni Geneviève (Institut Curie, FR)

Baubec Tuncay (University of Zurich, CH)

Bourch'is Déborah (Institut Curie, FR)

Boskovic Ana (EMBL, IT)

Buschbeck Markus (JC Leukaemia Research Institute, ES)

Coulon Antoine (Institut Curie, FR)

Dauphin Aurélien (Institut Curie, FR)

Delattre Olivier (Institut Curie, FR)

di Croce Luciano (Centre for Genomic Regulation, ES)

Dostatni Nathalie (Institut Curie, FR)

Drinnenberg Ines (Institut Curie, FR)

Dunleavy Elaine (Center for chromosome Biology, IE)

Harrison Paul Liam (NY, USA)

Iovino Nicola (Max Planck Institute, Frieburg, DE)

Le Baccon Patricia (Institut Curie, FR)

Lenstra Tineke (Netherlands Cancer Institute, NL)

Moore Andrew (Bioessays, DE)

Périé Leila (Institut Curie, FR)

Schneider Rob (Institute of Functional Epigenetics, DE)

Siegel Nicolai  (Ludwig-Maximilians University, DE)

Taddei Angela (Institut Curie, FR)

Van Ourdernaarden Alexander (Hubrecht Institute, NL)

Keynote speakers

Workman Jerry (Stowers Institute, USA)

This list of speakers may still change


Nathalie Dostatni, UMR3664, FlyTeam (Institut Curie / Sorbonne Université)

Geneviève Almouzni, UMR3664, FrogTeam (Institut Curie / CNRS)

Iva Simeonova, UMR3664, FrogTeam (Institut Curie / Sorbonne Université)

Scientific Committee

  • Geneviève ALMOUZNI
  • Antoine COULON
  • Nathalie DOSTATNI
  • Angela TADDEI