January 3rd
January 31st
International course

Development & Cancer

1st course "From Pigment Cells to Melanomas" - 2012

In humans, pigment cells comprise the neural crest-derived melanocytes and the pigmented retina cells. Tumor transformation in both cell types results in cutaneous or uveal melanomas, two usually aggressive and hard-to-treat tumour types.

This course will address the development, the differentiation and the migratory behaviour of melanocytes in embryos and melanoma formation and metastasis in adults. Focus will be made on cellular and molecular mechanisms controlling these processes. The course will then address how advanced imaging technologies, systems biology, and in vivo approaches have progressed in melanoma understanding in the last few years. Finally, some directions for therapeutic approaches will be developped. In the practical part of this course, the notions developped in the seminars and courses will be illustrated by in vivo manipulations in embryos and in vitro cellular manipulation, both followed by advanced imaging analysis.

Course in English


ECTS Information

Course format: Seminars (1 week, 5 ECTS)

& Practical Course (3 weeks, 5ECTS).

Practical Informations

There is no registration fee for this course
Institut Curie Centre de Recherche, Centre Universitaire 91405 Orsay, France
Université Paris Sud 11, Centre Universitaire, 91405 Orsay, France

Number of Participants

Course format: Seminars (1 week, limited to 12 students)

& Practical Course (3 weeks, limited to 25 students in addition to the 12 following the practical course).



Anne H. Monsoro-Burq, Patrick Pla, Simon Saule, Morgane Locker, Odile Bronchain


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