2016
January 11th
January 15th
Vignette
International course

Development & Cancer

from pigment cell development to melanomas_5th Course

The course presents the current knowledge in neural crest and melanocytes development (cell biology, transcriptomics, imaging...), as well as how melanocytes undergo tumor progression in adults. It ends with presentation of the most up-to-date therapeutical strategies.

In humans, pigment cells comprise the neural crest-derived melanocytes and the pigmented retina cells. Tumor transformation in both cell types results in cutaneous or uveal melanomas, two usually aggressive and hard-to-treat tumour types. This course will address the development, the differentiation and the migratory behaviour of melanocytes in embryos and melanoma formation and metastasis in adults. Focus will be made on cellular and molecular mechanisms controlling these processes. The course will then address how advanced imaging technologies, systems biology, and in vivo approaches have progressed in melanoma understanding in the last few years. Finally, some directions for therapeutic approaches will be developped.
In the practical part of this course, the notions developped in the seminars and courses will be illustrated by in vivo manipulations in embryos and in vitro cellular manipulation, both followed by advanced imaging analysis.

Course in English

Presentation

Objectives

To discuss the big questions in the field of Development and Cancer. To provide an up-to-date landscape on melanocyte biology, for master and doctoral students as well as for researchers.

Practical information

There is no registration fee for this course

 

 

Location
Institut Curie Centre de Recherche, Université Paris Sud, Centre Universitaire, 91405 Orsay, France.

Speakers

Organisers

Anne Hélène Monsoro-Burq, (Institut Curie and Université Paris Sud),
Simon Saule (Institut Curie and Université Paris Sud),
Patrick Pla (Institut Curie and Université Paris Sud),
Caroline Borday (Institut Curie and Université Paris Sud),
Frederic Coquelle (Université Paris Sud),
Laurence Méry (Institut Curie and Université Paris Sud).

Scientific Committee

Anne Hélène Monsoro-Burq, (Institut Curie and Université Paris Sud),
Simon Saule (Institut Curie and Université Paris Sud),
Patrick Pla (Institut Curie and Université Paris Sud),
Caroline Borday (Institut Curie and Université Paris Sud),
Frederic Coquelle (Université Paris Sud),
Laurence Méry (Institut Curie and Université Paris Sud).

With

Organisation

  • Training Unit - Institut Curie