Post-transcriptional Gene Regulation

Mechanisms and networks

The aim of this course is to provide an overview of post-transcriptional gene regulations at multiple steps, including notably (pre-)messenger RNA splicing, polyadenylation, stability and translation, this year with a focus on two emerging topics, mRNA localization and modifications (epitranscriptome).

In addition to lectures given by international experts in the field, the course will also rely on the active contribution of participants and on their interactions with speakers. Each participant will present his scientific project (poster, elevator pitch) and will co-chair a speaker. In addition to long discussion time after each talk, participants will have the opportunity to meet speakers every day at coffee breaks and lunch.

Registration deadline

February 19th 2017

Presentation
Documents and links
Practical information
Speakers

Presentation

Objectives

- Regulatory mechanisms of post-transcriptional steps of gene expression (mRNA splicing, polyadenylation, stability, translation, editing, methylation, localization…).
- Pan-genomic analysis of gene regulation beyond transcription (splicing arrays, RNA-Seq, CLIP-Seq, ribosome profiling…)
- Deregulation of post-transcriptional gene expression in pathologies.
- Focus of the year: mRNA modifications (epitranscriptome) and localization.

Undergraduate student