The aim of this course is to provide an overview of epigenetic mechanisms and their links to gene expression and chromatin dynamics in different systems. The diverse functions of the nucleus involving the genome and its organization will be discussed with an emphasis on technological limits and the new experimental approaches being developed today. Links between the disruption of nuclear functions and the development of human pathologies will be discussed.
This year is the 20th anniversary of this Curie International Course (the first one to be organized ever) and we have decided to make it a very special event. First, we will start with a one-day workshop with the EpiGen3Sys IRN, which builds on the network of excellence EpiGeneSys that supported many editions of the Course over the years. Second, most of our invited speakers will be Alumni from previous Courses, who are now group leaders in Epigenetics worldwide.
The main themes that will be treated are :
• Epigenetics and Chromatin Dynamics
• Imaging the Nucleus and its functions
• Silencing, transcriptional landscapes and genomics
• Memory of transcriptional states, stem cells and reprogramming
• Epigenetics: quantitative approaches and theoretical models
• maintenance of (Epi)genome integrity
• Epigenetics and Cancer
The success of the course relies on the contributions of participants who are expected to be proactive and to participate in all of the events organized including:
1. Presentation of their own scientific project with a poster
2. Participation in the Journal Club to both present and review key articles proposed by the speakers
3. Participation in the "career development" workshop during the Saturday morning and the "epi-Courses" such as the “Art & Science” workshop.
The success of the course relies on the contributions of participants who are expected to be proactive and to participate in all of the events organized including:
1. Presentation of their own scientific project with a poster
2. Participation in the Journal Club to both present and review key articles proposed by the speakers
3. Participation in the "career development" workshop during the Saturday morning and the "epi-Courses" such as the “Art & Science” workshop.
6 ECTS accredited by Sorbonne Université – Master BMC (UE MU5BM460)
Evaluation will be based on performance during the Journal Club, poster presentation and active participation during the Course.
Geneviève Almouzni - FR
Valérie Borde - FR
Maud Borensztein (Alumni 2005) - FR
Charlène Boumendil (Alumni 2011) - FR
Sigurd Braun - DE
Hervé Chneiweiss - FR
Antoine Coulon - FR
Aurélien Dauphin - FR
Pierre-Antoine Defossez - FR
Nathalie Dostatni - FR
Ines Drinnenberg - FR
Daniele Fachinetti - FR
Angelika Feldmann (Alumni 2011) - DE
Paul Liam Harrison - UK
Nicola Iovino - DE
Joanna Jachowicz (Alumni 2013) - AT
Patricia Le Baccon - FR
Raphael Margueron - FR
Leonid Mirny – US/FR
Guillermo Orsi (Alumni 2008) - FR
Angela Taddei - FR
Felipe Karam Teixeira (Alumni 2008) – UK
Céline Vallot (Alumni 2005) - FR
Geneviève ALMOUZNI
Nathalie DOSTATNI
Iva SIMEONOVA
Geneviève ALMOUZNI
Antoine COULON
Nathalie DOSTATNI
Ines DRINNENBERG
Daniele FACHINETTI
Leonid MIRNY
Iva SIMEONOVA
Angela TADDEI
This year is the 20th anniversary of this Institut Curie International Course.
40 participants
Selection will be made on CV, motivation, and recommendation.
