2020
September 21st
September 24th
Vignette
International course

SIREDO Course on Pediatric CNS Tumors

integrating scientific & clinical approaches

THIS COURSE IS POSTPONED UNTIL 2021 IN LIGHT OF THE COVID-19 PANDEMIC.

Central Nervous System (CNS) tumors are the second most common cancers in children after leukemia.

CNS tumors in children, adolescents and young adults are a very heterogeneous group of rare tumors. They are classified in embryonic tumors (medulloblastomas, ATRT, other embryonic tumors), high-grade or low-grade glial tumors, ependymomas, craniopharyngiomas, intracranial malignant germ cell tumors, as well as other rarer tumor types.

Their diagnosis is complex and requires a multidisciplinary approach involving highly specialized neuroradiology and neuropathology.

Over the past 20 years, and more particularly over the last 5 years, the advances in high-throughput molecular biology have allowed supplementing the histological classification with a molecular classification of the tumors. Molecular alterations - sometimes extremely specific- observed in these tumors include activation of signaling pathways, gene fusions or point mutations, and constitute very robust markers reinforcing the histological analysis.

These genetic alterations are often causative of the disease. Their functional study is essential to understand the mechanisms of tumor initiation and progression, and the development of relevant animal models is fundamental for the generation of new treatments.

There are several therapeutic issues:

- In terms of survival, CNS tumors have become the leading cause of death from cancer in children and a major cause of death in adolescents and young adults

- In terms of quality of survival, the risk of sequelae linked to the disease and to its related treatments is maximal due to the damage affecting the developing nervous system.

 

To view the program please click here

Course in English
Registration deadline

Présentation

Objectifs

The SIREDO center ( for Care, Innovation, Research in Childhood Cancer, ADOlescent and young adults) of Institut Curie organizes this course with clinicians and researchers from Institut Curie,  Gustave Roussy, Necker Hospital and Sainte-Anne Hospital. Renowned researchers and clinicians from Heidelberg, Toronto, London and Lyon are also invited to participate to this multidisciplinary course. The program covers an up-to-date clinical-biological approach to diagnosis and treatment.

The course is open to all medical disciplines involving diagnosis and treatments in pediatric neuro-oncology (pathologists, biologists, radiologists, neurosurgeons, pediatric oncologists / neuro-oncologists, radiotherapists, neuro-pediatricians, etc.) as well as Master 2 students, PhD students and post-doctoral fellows already working in the field or wishing to join it.

Informations pratiques

Selection result
1 July 2020
There is no registration fee for this course
Lieu
Bâtiment de Biologie du Développement
<p>30-40 participants</p>

Effectif maximum

40 people

Effectifs

30-40 participants

Conditions de selection

Selection based on CV

Intervenants

Intervenants

ALAPETITE Claire - FR

AYRAULT Olivier - FR

BECCARIA Kevin - FR

BODDAERT Nathalie - FR

BOLLE Stephanie - FR

BOUFFET Eric - CA

BOURDEAUT Franck - FR

BRISSE Hervé - FR

DANGOULOFF-ROS Volodia - FR

DOZ François - FR

DUFOUR Christelle - FR

FRAPPAZ Didier  - FR

FRUHWALD Michael - DE

GRILL Jacques - FR

HABERLER Christine - AT

HUANG Annie - CA

HULLEMAN Esther - NL

JABADO Nada - CA

JONES David - DE

JONES Chris - UK

KOOL Marcel - DE

LEGER Juliane - FR

MARTINEZ-BARBERA Juan Pedro - UK

PEET Andrew - UK

PFISTER Stephan - DE

POSTEL-VINAY Sophie - FR

POUPONNOT Celio - FR

PUGET Stéphanie - FR

TAYLOR Michael - CA

VARLET Pascale - FR

WILLIAMSON Daniel – UK

Keynote speakers

This list of speakers may still change

Comité scientifique

ALAPETITE Claire
AYRAULT Olivier
AZZI-HATEM Sandy
BODDAERT Nathalie
BOLLE Stephanie
BOURDEAUT Franck
DELATTRE Olivier
DOZ François
DUFOUR Christelle
GRILL Jacques
POUPONNOT Celio
PUGET Stéphanie
VARLET Pascale
 

Organisation

  • Care, Innovation and Research in Paediatric, Teenage and Young Adult Oncology